Optimized Route for the Synthesis of Derivative of Phenylalanine-azobenzene

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Jie Chen
Gao He
Liangchun Li


In this paper, the derivative of phenylalanine-azobenzene was synthesized from p-nitrobenzoic acid and L-ethyl benzoate by condensation, ferric acid reduction and aromatic amine oxidation, and the key compounds were characterized by 1H-NMR and MS. At the same time, we optimized the synthetic route. And the optimized route increased the total yield of target molecule by 10.28%.

Azobenzene derivative, aromatic amine oxidation, nitro reduction, photoresponsiveness

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How to Cite
Chen, J., He, G., & Li, L. (2019). Optimized Route for the Synthesis of Derivative of Phenylalanine-azobenzene. International Research Journal of Pure and Applied Chemistry, 18(4), 1-5. https://doi.org/10.9734/irjpac/2019/v18i430095
Original Research Article