Polar Diels-Alder Reactions Using Heterocycles as Electrophiles. Influence of Microwave Irradiation

Maria N. Kneeteman

Department of Chemistry, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santiago del Estero 2829, 3000 Santa Fe, Argentina and National Council of Scientific and Technical Research (CONICET), Argentina

Anna F. López Baena

Department of Chemistry, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santiago del Estero 2829, 3000 Santa Fe, Argentina

Claudia Della Rosa

Department of Chemistry, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santiago del Estero 2829, 3000 Santa Fe, Argentina

Pedro M. E. Mancini *

Department of Chemistry, Facultad de Ingeniería Química, Universidad Nacional del Litoral, Santiago del Estero 2829, 3000 Santa Fe, Argentina

*Author to whom correspondence should be addressed.


Abstract

In this work we studied a series of polar Diels-Alder reactions using different heterocycles derivatives acting as electrophiles joint to dienes of different nucleophilicity, analyzing the effect of the microwave irradiation in these processes. We employ the technique in two conditions: benzene as solvent and solvent free reactions. The last one presents the better yield in shorter time of reaction. Using microwave heating the aromatic cycloadducts are clearly predominant. It is possible to demonstrate that the microwave irradiation has a better influence on these cycloaddition reactions respect to those developed in thermal classical conditions.

 

Keywords: Aromatic heterocycles, electrophiles, microwave irradiation, solvent free, Diels-Alder


How to Cite

N. Kneeteman, Maria, Anna F. López Baena, Claudia Della Rosa, and Pedro M. E. Mancini. 2015. “Polar Diels-Alder Reactions Using Heterocycles As Electrophiles. Influence of Microwave Irradiation”. International Research Journal of Pure and Applied Chemistry 8 (4):229-35. https://doi.org/10.9734/IRJPAC/2015/18867.

Downloads

Download data is not yet available.