Main Article Content
A series of five 8-azacoumarin derivatives bearing aryl moieties at C-5 and C-7 designed and synthesised by a concise procedure utilising grinding and ultrasound approaches. The multi-component protocols proceeded smoothly in the absence of solvent to furnish the target products in moderate to good yields. All the synthesised molecules characterised via 1HNMR, 13CNMR, IR, Mass spectra, and elemental analyses. In this article, we examined the insecticidal activity of some of the synthesized 8-azacoumarin derivatives as a new trend to the control cotton leafworm Spodoptera littoralis that considered the most serious attacking pest on cotton.