Fe3+-Montmorillonite K10 as an Efficient, Green and Reusable Heterogeneous Catalyst for Synthesis of Mannich Type Reaction under Solvent-free Condition
Suneeta Bhandari *
Organic Synthesis Laboratory, Department of Chemistry, G. B. Pant University of Agriculture and Technology, U.S. Nagar, 263145, India
Virendra Kasana
Organic Synthesis Laboratory, Department of Chemistry, G. B. Pant University of Agriculture and Technology, U.S. Nagar, 263145, India
*Author to whom correspondence should be addressed.
Abstract
A simple and efficient one-pot three-component synthesis of Mannich type reaction has been developed using recyclable Fe+3-montmorillonite K10 (Fe+3@K10) under solvent-free condition. The reaction of aromatic aldehydes, aromatic anilines and aryl ketones produced β-amino carbonyl derivatives in good to excellent yields. The developed method making use of a recyclable catalyst is economical and eco-friendly and affords good yields under mild reaction conditions.
Keywords: Fe 3-montmorillonite K10, Mannich reaction, heterogeneous, recyclable, solvent free