Synthesis and Characterization of Thiazolo Pyridin-2-Amine and Their Schiff Bases
Mangesh Vijay Sonawane *
Department of Chemistry, R.C. Patel ACS College, Shirpur Dhule, Maharashtra, India.
Sandip Balu Chaudhari
Department of Chemistry, R.C. Patel ACS College, Shirpur Dhule, Maharashtra, India.
Jaywant Prakash Sonawane
Department of Chemistry, R.C. Patel ACS College, Shirpur Dhule, Maharashtra, India.
Suryakant Sudhakar Patil
Department of Chemistry, R.C. Patel ACS College, Shirpur Dhule, Maharashtra, India.
Mahesh Rajendra Sonawane
Department of Chemistry, R.C. Patel ACS College, Shirpur Dhule, Maharashtra, India.
Anil Vinayak Patil
Department of Chemistry, R.C. Patel ACS College, Shirpur Dhule, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
The efficient synthesis of thiazolo pyridine 2-amine(3) by reaction of 2-amino pyridine with ammonium thiocyanate(2). The reaction carried out in presence of ceric ammonium nitrate and Dimethyl Sulphoxide as a solvent. The aromatic aldehyde reacts with synthesized compound thiazolo pyridin-2-amine (3) by using catalytic amount of Ni (NO3)2 .6H2O at room temperature. Advantages of this protocol are its very good yields.
Keywords: Ceric ammonium nitrate, thiazolo pyridin-2-amine, Ni (NO3)2 .6H2O.