Identification of Compounds in the Ethyl Acetate Fraction of Hyptis suaveolens Leaves by HPLC-ESI- Q-TOF -MS/ MS Analysis
Mabintou Kalo *
Sciences and Technology Training and Research Unit, UFR-ST, University Alassane Ouattara, Bouaké, Ivory Coast and Laboratory of Industrials Synthesis Processes, Environment and New Energies (LAPISEN), National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast.
Amon Diane Marina N’Tamon
Department of Analytical, Mineral and General Chemistry, Food Technology, Felix Houphouët-Boigny University, Abidjan, Ivory Coast and UFR Pharmaceutical and Biological Science, Felix Houphouët-Boigny University, Abidjan, Ivory Coast.
Brahima Soumahoro *
Department of Agro-food Chemical Engineering, National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast and Laboratory of Industrials Synthesis Processes, Environment and New Energies (LAPISEN), National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast.
Ali Sanou
Department of Agro-food Chemical Engineering, National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast and Laboratory of Industrials Synthesis Processes, Environment and New Energies (LAPISEN), National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast.
Philatryho Atché
Department of Agro-food Chemical Engineering, National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast and Laboratory of Industrials Synthesis Processes, Environment and New Energies (LAPISEN), National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast.
Yaya Soro
Department of Agro-food Chemical Engineering, National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast and Laboratory of Industrials Synthesis Processes, Environment and New Energies (LAPISEN), National Polytechnic Institute Felix Houphouët-Boigny, Yamoussoukro, Ivory Coast.
Barthélémy Attioua
Department of Physics Chemistry, Felix Houphouët-Boigny University, Abidjan, Ivory Coast and Laboratory of Constitution and Matter Reaction (LCRM), UFR-SSMT, Felix Houphouët Boigny University, Abidjan, Ivory Coast.
*Author to whom correspondence should be addressed.
Abstract
Hyptis suaveolens is a plant of Ivory Coast flora. Preliminary studies have shown that the plant's leaves possess multiple medicinal properties, certainly due to the presence of terpenic and phenolic compounds. Yet, the plant's leaves compounds structures have been fewest elucidated. This study aim to determine the structures of a number of known compounds present in the ethyl acetate fraction obtained from the hydroethanol extract of Hyptis suaveolens leaves. Thus, fifteen known compounds structures were identified in ethyl acetate fraction of the plant's leaves by dereplication method. Nine of these compounds, are phenolic compounds and the others are terpenoids. Five of these compounds had not yet been elucidated in the leaves of Hyptis suaveolens. All these bioactive molecules in Hyptis suaveolens leaves makes this plant an alternative for combating many diseases caused by oxidative stress.
Keywords: Hyptis suaveolens, dereplication, compound structures, ethyl acetate fraction