Bioactive Components and Antioxidative Activity of the Rosae Pseudo–Fructus
Emina Avdić
Faculty of Pharmacy, University of Tuzla, Urfeta Vejzagića 8, 75000 Tuzla, Bosnia and Herzegovina.
Aida Smajlagić *
Department of Chemistry, Faculty of Natural Sciences and Mathematics, University of Tuzla, Urfeta Vejzagića 4, 75 000 Tuzla, Bosnia and Herzegovina.
Merima Ibišević
Faculty of Pharmacy, University of Tuzla, Urfeta Vejzagića 8, 75000 Tuzla, Bosnia and Herzegovina.
Maida Šljivić Husejnović
Faculty of Pharmacy, University of Tuzla, Urfeta Vejzagića 8, 75000 Tuzla, Bosnia and Herzegovina.
Lamija Kolarević
Faculty of Pharmacy, University of Tuzla, Urfeta Vejzagića 8, 75000 Tuzla, Bosnia and Herzegovina.
Emir Horozić
Faculty of Technology, Univerzitetska 8, Tuzla, Bosnia and Herzegovina.
Alma Salkić
Zada Pharmaceuticals, Bistarac Donji bb, 75300, Lukavac, Bosna and Herzegovina.
Amra Butković
Zada Pharmaceuticals, Bistarac Donji bb, 75300, Lukavac, Bosna and Herzegovina.
Ermina Cilović Kozarević
Faculty of Pharmacy, University of Tuzla, Urfeta Vejzagića 8, 75000 Tuzla, Bosnia and Herzegovina.
*Author to whom correspondence should be addressed.
Abstract
The fruit of Rosa canina (rosehip) has long been used in traditional medicine, and recent studies confirm its health benefits due to its content of flavonoids, carotenoids, fatty acids, and high vitamin C levels. This study examined three preparations: infusion, ultrasound-assisted extract, and traditional jam. Total phenols were measured using the Folin-Ciocalteu method, and antioxidant activity by the DPPH method. The highest total phenolic content was observed in the infusion of dried fruit (163.477 mg GAE/l), followed by the fruit extract (44.932 mg GAE/l), with the jam extract showing the lowest content (23.477 mg GAE/l). Antioxidant activity was assessed via DPPH inhibition percentage and IC50 values to identify the most effective form of compounds. The findings suggest that infusion of dried rosehip fruit provides the highest antioxidative capacity, highlighting its potential as a functional food ingredient.
Keywords: Rosae pseudo-fructus, extraction, bioactive components, antioxidative activity, DPPH